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Brian Leyland- Jones MD, PhD


Vice President, Molecular Experimental Medicine


Avera Cancer Institute Center for Precision Oncology and Department of Molecular and Experimental Medicine


Sioux Falls, SD


The New York Hospital
Memorial Sloan-Kettering Cancer Center
Memorial Hospital


Dr. Brian Leyland-Jones, is the Chief Medical Officer and Scientific Advisory Board member for the National Foundation for Cancer Research. He also serves as the Chief Medical Officer of OTraces, SCITech Development and the N OF 1 Mission. Dr. Leyland-Jones is also the CSO of the Darwin Foundation, collectively devoted to the implementation of prevention and cure of malignancy globally. He sits on several national and international boards, including the Asian Foundation for Cancer Research (AFCR), NED Biosystems, Non-Pareil, and Ratio and is Director Emeritus of the WIN Consortium. He founded Xanthus, AKESOgen, and Viviphi.

Dr. Leyland-Jones holds biochemistry, medical, and doctoral degrees from the University of London. Following residency training at Hammersmith, Brompton, St. Bartholomew’s, and London hospitals, he completed a clinical pharmacology fellowship at Cornell University and a medical oncology fellowship at Memorial Sloan-Kettering Cancer Center. He then joined the academic staff at Memorial Sloan-Kettering Cancer Center and New York Hospitals with a special research interest in early-phase clinical development, clinical pharmacology, and biomarker evaluation of many anticancer compounds, including the platinum-containing agents and anthracycline analogs in use today.

Dr. Leyland-Jones has held positions at the National Cancer Institute, McGill University Comprehensive Cancer Centre, and Emory University. As Director of the Winship Cancer Center and Associate Vice President of Health Sciences, Dr. Leyland-Jones led the Center to obtain National Cancer Institute Cancer Center Designation, the first in the State of Georgia, and for the first time in 30 years. Dr. Leyland-Jones was instrumental in building the Genomics Medicine Program at the Avera Cancer Institute in Sioux Falls, SD where he was the Vice President of Molecular and Experimental Medicine from 2014-2019.

Dr. Leyland-Jones is the recipient of numerous research grants and has served as principal investigator, co-principal investigator, and co-investigator on more than 100 clinical studies. He has authored and co-authored more than 210 peer-reviewed articles and book contributions, 25 books and book chapters, 425 abstracts, and 35 patents. He has a robust speaking and private consulting practice that takes him all over the world.